Seyyid Burhânüddîn Hüseyn Muhakkık-ı Tirmidhi was born in District of Tirmidhi in 1166 or 1169. His dynasty is based on Hazrat Hussein. He is known by the nickname "sayyid-i sirdân", because he was included in the lineage of Sayyid and Hüseynî, as well as knowing the secrets in the hearts or foretelling the arrival of Şems-i Tebrizî in Konya to Mevlânâ Celâleddîn-i Rûmî. As mentioned by Mevlana, he is also known with the nickname "Burhaneddin", "burhan-i din", "burhan" and "muhaqkik", which indicates that he is a competent Sufi.
The tomb of Seyyid Burhaneddin was built in 1892 by the Governor of Kayseri, Mehmet Nazım Pasha, with the help of the Ankara Governor Abidin Pasha. The tomb has a square plan, is made of cut stone, and is covered with a dome. Although the tomb was built at the end of the 19th century, it is in the Seljuk style and is located in the large cemetery named after him on Talas Street.
Inside the tomb, there is a sarcophagus of Seyyid Burhaneddin in the form of a half cylinder under the dome. At the head of the sarcophagus is a poetic work titled (Ayine-i Seyyid-i Sırdan) written by Ahmed Remzi Dede from Kayseri, one of the Mevlevi sheikhs, about Sayyid. There is also the tomb of Seyyid Zeynelabidin, who died in Kayseri in 1414, one of the grandchildren of the Prophet.
There are Mevlevi tombstones to the left of the tomb entrance. Among them are the tombs of Kayseri Mevlevi Sheikh Süleyman Turabi (1835), the sheikh's son Hacı Remzi Efendi (1865), Ahmet Remzi Efendi's son Süleyman Ataullah (1904) and Ahmet Remzi Dede (1944).
There is the tomb of Emir Erdoğmuş in the south and adjacent to the tomb.
There are tombdar (a kind of servant) rooms built in later periods around the tomb. The management of the tomb has been transferred to the Kayseri Museum Directorate since 1981.
The Tomb of Seyyid Burhaneddin, the teacher of Mevlana Celaleddin Rumi, who spent the last years of his life in Kayseri, is one of the most visited tombs in Kayseri today.